SCNN1, an Epithelial Cell Sodium Channel Gene in the Conserved Linkage Group on Mouse Chromosome 6 and Human Chromosome 12
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چکیده
منابع مشابه
Perfect conserved linkage across the entire mouse chromosome 10 region homologous to human chromosome 21.
The distal end of human Chromosome (HSA) 21 from PDXK to the telomere shows perfect conserved linkage with mouse Chromosome (MMU) 10. This region is bounded on the proximal side by a segment of homology to HSA22q11.2, and on the distal side by a region of homology with HSA19p13.1. A high-resolution PAC-based physical map is described that spans 2.8 Mb, including the entire 2.1 Mb from Pdxk to P...
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A cDNA clone for human immune interferon (IFN-gamma) gene sequences, plasmid p69, was used to chromosomally map the IFN-gamma gene by detecting human IFN-gamma gene sequences in DNA isolated from human-rodent somatic cell hybrids. We were able to map the IFN-gamma gene by correlating the human chromosomes present in these hybrids with the human specific 8.8 and 2.0 kilobase pair fragments produ...
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Comparison of human sequences with the DNA of other mammals is an excellent means of identifying functional elements in the human genome. Here we describe the utility of high-density oligonucleotide arrays as a rapid approach for comparing human sequences with the DNA of multiple species whose sequences are not presently available. High-density arrays representing approximately 22.5 Mb of nonre...
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Protein tyrosine phosphatases (PTPases) regulate the tyrosine phosphorylation of target proteins involved in several biological activities including cell proliferation and transformation. Protein tyrosine phosphatase E (PTPE) contains duplicated PTPase-like domains and a short extracellular region. Using the fluorescence in situ hybridization method, the gene encoding PTPE (locus symbol Ptpre...
متن کاملThe identification of the chromosome bearing linkage group XII in the mouse.
0 date, it has been impossible to assign specific linkage groups of the mouse 'to specific chromosomes because of the lack of distinguishing morphological characteristics among the chromosomes. The 40 acrocentric chromosomes (2n=40) all blend into a continuous array when arranged by size. Several workers have reported that a few chromosomes show subtle morphological differences (FORD et al. 195...
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ژورنال
عنوان ژورنال: Genomics
سال: 1994
ISSN: 0888-7543
DOI: 10.1006/geno.1994.1599